NBS Supplement in Women with Depression and Obesity: RCT

Article Title

Nutrition and Food Science Nutrition Bio Shield (NBS) supplement effects on Depression, Anxiety, Stress, and Food craving in women with depression and obesity: a double-blind Randomized Controlled Trial

Journal: Nutrition and Food Science

Link: https://doi.org/10.1108/NFS-04-2022-0127

Publication Date: September 2022

Corresponding Author: Seyed-Ali Mostafavi

Depression, anxiety, stress, and an increased tendency towards food cravings are common mental health challenges in individuals dealing with both depression and obesity, presenting significant difficulties for women. In this text, we will explore the effects of these issues on women affected by both depression and obesity.

Section One: Depression and its Effects on Women

Depression is a mental health condition that can have profound effects on an individual's life. Women experiencing depression may grapple with negative emotions, reduced energy levels, and a loss of interest in daily activities. This situation can lead to nutritional challenges and negatively impact physical health.

Section Two: Anxiety and its Impact on Nutrition

Anxiety is another significant factor contributing to nutritional problems in women with obesity and depression. Individuals with anxiety may be inclined towards emotional eating, unconsciously consuming unhealthy foods. These behaviors can lead to weight gain and exacerbate physical health issues.

Section Three: Stress and its Consequences on Nutrition

Stress plays a crucial role in exacerbating nutritional challenges for women with depression and obesity. Stress may increase the tendency towards unhealthy eating habits and poor food choices. Additionally, stress can impede the weight loss process and intensify weight-related problems.

Section Four: The Effects of Obesity on Mental Health and Nutrition

Obesity itself contributes to a myriad of mental health and nutritional challenges. The physical implications of obesity can lead to a negative self-image and contribute to the cycle of depression and stress. Furthermore, the challenges associated with weight management may exacerbate existing mental health issues and disrupt healthy nutritional practices.

In the intricate landscape of women's mental health and obesity, this study explores the intertwined dynamics of depression, anxiety, stress, and food craving. Recognizing the reciprocal relationship between psychological well-being and physical health, our multidimensional approach integrates psychological assessments, physiological markers, and qualitative insights to comprehensively unravel the complexities within this specific demographic. By acknowledging the unique gender-specific factors at play, our research aims to contribute nuanced insights into the bidirectional influence of depression and obesity in women. The overarching goal is to inform targeted interventions and holistic care strategies, addressing the distinct challenges faced by these individuals and fostering a more integrated approach to enhance their mental and physical well-being.

The study investigates the impact of a natural supplement, Nutrition Bio Shield (NBS), derived from whole wheat grains, on depression, anxiety, stress, and food craving in women with depression and obesity. The double-blind randomized controlled trial involved 56 participants with a Body Mass Index (BMI) ≥ 25 and mild or moderate depression. The NBS group received 5 grams of the supplement daily, while the placebo group received a similar-looking placebo. Assessments were conducted at baseline, 4 weeks, and 8 weeks.

Results indicate that after four weeks, stress significantly reduced in the NBS group, and after eight weeks, anxiety, stress, and food craving significantly decreased compared to the placebo. The multivariate analysis confirmed the significant effects of NBS in reducing anxiety and stress after controlling for demographic variables. There were no significant differences in side effects between the NBS and placebo groups.

The NBS supplement, enriched with vitamins, minerals, and bioactive compounds, demonstrated efficacy in reducing stress and anxiety. The study suggests that the supplement's broad spectrum of micronutrients may contribute to its positive effects on mental health. The findings highlight the potential of whole-grain-based functional food supplements in addressing mental health issues, particularly in populations with comorbidities of obesity and depression.

Key Points:

• NBS supplement, derived from whole wheat grains, reduced stress and anxiety in women with depression and obesity.
• Significant reductions in stress, anxiety, and food craving were observed after eight weeks of NBS supplementation.
• The broad spectrum of micronutrients in NBS may contribute to its positive effects on mental health.
• The supplement was safe, with no significant differences in side effects compared to the placebo.