Antimicrobial Properties of NBS Superfood

Article Title

Antimicrobial Properties of a Type of Drug Supplement: Nutrition Bio-Shield Superfood

Journal: International Journal of Nutrition and Food Engineering

Link: https://publications.waset.org/10013285/pdf 

Publication Date: November 2023

Corresponding Author: Azam Bayat

Antibiotic resistance is a serious global health problem that threatens the effectiveness of modern medicine. Antibiotic resistance occurs when bacteria evolve to resist the drugs that are used to treat them, making infections harder or impossible to cure. This can lead to increased disease spread, severe illness, disability and death. According to the World Health Organization, antibiotic resistance was directly responsible for 1.27 million global deaths in 2019 and contributed to 4.95 million deaths. Some of the factors that contribute to antibiotic resistance are the misuse and overuse of antibiotics in humans, animals and plants, the lack of new antibiotics in the research and development, and the lack of access to quality diagnosis and treatment of infections. To combat antibiotic resistance, we need to prevent infections, use antibiotics wisely, and invest in innovation and research.

Antibiotic therapy is often used to treat bacterial infections, but it can have drawbacks such as side effects, allergic reactions, and antibiotic resistance. A possible alternative or complementary approach is to use supplements that enhance the immune system, which is the body’s natural defense against pathogens. Some supplements that may boost immune function include vitamin C, vitamin D, zinc, and probiotics. These supplements may have antibacterial, anti-inflammatory, antioxidant, and immunomodulatory properties that can help prevent or fight infections. However, supplements are not a replacement for prescription medication and should be used with caution and under medical supervision.

As the world battled with the rising prevalence of infectious diseases, scientists searched for new ways to combat them. One such way was through the development of a new dietary supplement, the Nutrition Bio-Shield Superfood (NBS). The NBS supplement was making it an organic biomaterial with potential antimicrobial properties.

A team of researchers decided to conduct a trial research to evaluate the effectiveness of the NBS supplement in inhibiting the growth of common bacteria involved in infectious diseases of the human body. The study involved testing the simple effect of different concentrations of NBS on the inhibitory diameter of bacterial growth.

The team began by collecting various bacterial strains from the collection center of clinical microorganisms in their country. The strains included Streptococcus mutans, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, and many more. The researchers transferred the bacterial strains to their microbiology laboratory to begin the experiment.

In the laboratory, the researchers prepared different concentrations of the NBS supplement and tested each concentration on the bacterial strains. The results were astounding. The highest diameter of the halo was observed at the concentration of 100 mg/ml, while the least was observed at 12.5 mg/ml. The NBS supplement had a significant inhibitory effect on the growth of the bacterial strains.

This study shows the results of an experiment that tested the antibacterial activity of a drug supplement against some common gram-positive and gram-negative bacteria involved in infectious diseases of the human body. The drug supplement was applied at four different concentrations: 12/5, 25, 50, and 100 mg/mL. The diameter of the non-growth halo around the drug-impregnated disk was measured as an indicator of the inhibitory effect of the drug supplement on the bacterial growth. The table also compares the diameter of the non-growth halo produced by the drug supplement with that of a standard drug for each bacterial strain. The standard drugs used were chlorhexidine for gram-positive and gram-negative bacteria, nystatin for Candida species, and cephalexin for Acinetobacter calcoaceticus and other gram-positive bacteria.

The results reveal that the drug supplement had a variable antibacterial activity depending on the bacterial strain and the concentration of the drug supplement. Some bacteria, such as Streptococcus sanguis, Streptococcus sobrinus, Pseudomonas aerogenosa, and Proteus mirabilis, were resistant to the drug supplement at all concentrations. Some bacteria, such as Streptococcus mutans, Escherichia coli, Klebsiella pneumoniae, Candida albicans, and Candida glabrata, showed a dose-dependent response to the drug supplement, with higher concentrations producing larger non-growth halos. Some bacteria, such as Streptococcus salivarius, Eikenella corrodens, Candida tropicalis, Staphylococcus aureus, Enterobacter aerogenesis, Citrobacter freundii, Staphylococcus saprophyticus, S. epidermitis, Enterococcus faecalis, Bacillus cereus, and Bacillus subtilis, showed a threshold response to the drug supplement, with a minimum concentration required to produce a non-growth halo. The table also shows that the drug supplement had a comparable or superior antibacterial activity to the standard drugs for most of the bacterial strains, except for Candida species, which were more sensitive to nystatin than to the drug supplement.

They tested the supplement on different bacterial strains, including those that were resistant to traditional antibiotics. The results showed that the NBS supplement had broad-spectrum antimicrobial properties, making it potentially useful in the treatment of infectious diseases caused by different types of bacteria.

In the end, the trial research conducted by the team of scientists had significant implications for the future of antimicrobial therapy. The NBS supplement represented a new and promising approach to combat the rising prevalence of infectious diseases worldwide.